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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21A
All Species:
1.82
Human Site:
T650
Identified Species:
5
UniProt:
Q641Q2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q2
NP_001005751.1
1341
147184
T650
G
E
P
R
D
S
G
T
L
Q
S
Q
E
A
K
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
Q738
P
R
D
S
G
T
L
Q
S
Q
E
A
K
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
G561
S
I
F
D
D
E
E
G
D
L
F
K
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
A644
G
E
L
W
D
S
G
A
T
Q
G
Q
E
A
K
Rat
Rattus norvegicus
Q80X08
1328
145131
N642
E
R
W
D
A
G
T
N
Q
G
Q
E
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
T637
D
P
A
K
P
S
S
T
I
S
Q
A
K
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
P745
Q
T
E
E
N
V
S
P
V
N
P
P
T
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
K924
E
K
K
K
E
E
K
K
K
E
E
K
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
65.9
N.A.
73.5
72.7
N.A.
N.A.
55.4
N.A.
21.7
N.A.
20.4
N.A.
N.A.
24.1
Protein Similarity:
100
92.6
N.A.
70.6
N.A.
80.5
80
N.A.
N.A.
68.7
N.A.
26.2
N.A.
36.6
N.A.
N.A.
36.2
P-Site Identity:
100
13.3
N.A.
13.3
N.A.
66.6
0
N.A.
N.A.
20
N.A.
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
N.A.
20
N.A.
66.6
6.6
N.A.
N.A.
40
N.A.
0
N.A.
13.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
0
0
12
0
0
0
23
12
45
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
23
34
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
23
23
12
12
12
23
12
0
0
12
23
12
45
12
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
23
0
0
0
12
12
23
12
0
12
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
12
23
0
0
12
12
12
0
0
23
23
34
34
% K
% Leu:
0
0
12
0
0
0
12
0
12
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
12
0
0
0
0
0
% N
% Pro:
12
12
12
0
12
0
0
12
0
0
12
12
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
12
12
34
23
23
0
0
0
% Q
% Arg:
0
23
0
12
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
12
0
34
23
0
12
12
12
0
0
0
0
% S
% Thr:
0
12
0
0
0
12
12
23
12
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
23
% V
% Trp:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _